Of note is the fact that, because of PEA’s high lipophilicity, micronized or ultra-micronized formulations are considered to get a lot more quickly absorbable, with far more favorable pharmacokinetics and higher efficacy. While there is some proof supporting this theory, there remains to be no evidence from the superiority of micronized PEA [sixt
2016a). This smaller sized enhance was proportionate to the scaled-down peak of PEA stages detected in human volunteers as opposed with beagle pet dogs. This big difference, consequently, is often a result of the decreased whole amount of PEA acutely administered to human volunteers (about ∼5 vs. thirty mg·kg−one in pet dogs) also to The real
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